Step 1: Hold Down
Make sure that the acrylic is held down securely. If it's not it can vibrate or flex ruining your cut altogether or marring the finish. On a T-Slot tabletop,with a sacrificial board, a few strips of double sided tape on the back side will go a long way to secure the piece. If you prefer, you can also use spray adhesives. Just make sure that the chemical properties are suitable for acrylic. A Vacuum Hold Table can make things easier, but if you're cutting pieces with a small surface area you may want to take these precautions as well.
Step 2: Bits
When cutting Acrylic, you won't get the best result using wood cutting bits, as cutting and chip removal are much more important. We recommend using a bit designed for Acrylic cutting. Our customers typically get the best results using "O-Flute" End Mill Bits.
While you can use bits of all sizes, it's generally advisable to use the largest bit possible for your design, as this increases depth possible, stability and removal of waste material.
Make sure that your bits stay sharp, as a dull bit will not give you the edges you want.