The following is what I came up with. There are many ways this could be improved, but this project served as a functional proof of concept for me, and I will make some changes the next go-around.
This frame was made to accommodate a queen-size mattress, but obviously the dimensions can be adjusted to suit your needs, or use the techniques for any number of other projects. I also made a couple of bedside tables in similar construction, for a later instructable.
*Please leave a comment if you have a suggestion that could improve this instructable, it is my first and I put it together rather hastily in order to submit it before the close of the WOODWORKING CONTEST, please vote if you like it!
Step 1: Recommended Tools