Step 1: Print This Stuff Out and Cut It Apart
Step 2: Play!
The Object of the game is to get rid of all your cards. First, divide the deck between everybody equally. (Or Half of it, if you're playing with a group of 2 or 3 people) Then start a story. You could Google for story-starters, but you can just start one from your own mind. (and Deck) Then, you must put down as many cards as you can within 5 sentences. First one out wins.
That was easy, right?
Step 3: Variations
Center your deck around a genre (Sci-Fi, Action)
Center your deck around a TV show, book, or movie that everyone is familiar with.
Use only single-word cards.
Use only action cards.
Or you could even twist the rules a little:
Find a way to be able to gain cards back
Limit the number of cards you can put down in one turn
Place a time-limit
Increase or decrease the sentience-limit