Now that 3D printing in transparent materials is widely available, we really can start having fun with models playing with light. There's also super convenient ways to use high numbers of RGB LEDs with the Arduino, using Adafruit's Neopixels which only need one digital pin for example.
This Instructable, describes how you can bring life to your favorite models (in my case, fruit fly brains ^^) by lighting them up, using optical fibers placed throughout the volume which create a nice 3D light show. I give a little bit more context about this project on my webpage.
Software and files