First off, I'd like to say that I wouldn't be the obscure but capable webcomic creator I am if it weren't for a whole slew of artists before me. My comic, HOSERS: The Comic Strip was inspired by my personal faves of the early greats of webcomicdom, primarily GOATS: The Comic Strip, GPF Comics, College Roomies From Hell!!!, and Nukees!. Thank you, Jon, Jeff, Maritza and Gav. As always I must tip my hat to you and your dedication to the art.
Second, anyone really interested in creating comics should pick up and read two or three of Scott McCloud's books: Understanding Comics, Reinventing Comics, and Making Comics. All are available from Amazon.com or you local bookstore. McCloud is very astute and has great suggestions on putting together a comic. If you read only two, you can omit "Reinventing Comics" -- but really, you should read all three. Also for good practice on framing comic strip panels, try out Wally Wood's 22 Panels That Always Work.
UPDATE: In addition to the books and sites above, you should also purchase and read the excellent How to Make Webcomics by Brad Guigar, Dave Kellett, Scott Kurz, and Kris Straub. It is an excellent book and I highly recommend it.
Anyway, this instructable will deal with the useful mechanics of webcomics production, in my opinion: how to sketch and ink your comic on paper. I plan a future instructable about how to make it into a nice-looking image for web - and possibly print - presentation. (Coming Soon!)
The process I use cribs parts from a dozen other webcomic processes, and of course doesn't apply to work drawn entirely on the computer, say using a tablet. I do that also, and will create a separate instructable for my fully-digital production methods if someone would like to see one.
So let's get started! For this tutorial, I am going to draw a comic strip. Well, don't act so surprised....