The first step is to gather the material.
Nintendo ES ROM Reader
Nintendo ES ROMS (I recommend Super Mario Bros.)
Computer, of course.
Windows Compatible Joystick or Controller (Optional)
Step 1: Okay, lets get started.
When you open up the Nintendo ES (NES) Rom Reader, it should be a small black window. Maximize it, then go to File > Open in the Top Left Corner.
Select your ROM. I chose Super Mario Brothers, as it was the best Video Game around back then.
When you load the ROM, press the Alt and Enter keys at the same time. This will enable Arcade, or, "Fullscreen" mode.
Step 2: Get your Game Set-Up.
Your game should now be set up and ready to play! Here are the controls. See the image below for the references to the classic NES controller.
Enter = Start, Select
Arrow Keys = Joypad (Control Pad)
Z = A
X = B
Enjoy your Nes'd PC!
But wait, there is more? Check out the next step to see.
Step 3: Controllers
You may have the desire to set up a Windows Compatible Controller to your PC. No problem. On the back of your Computer, there should be a Long or Small Port with Holes in it. This is your Game Controller port. On my Computer, it is right beside my Video / Webcam cable ports.
When you plug in your compatible controller, or whatever fits in there, go to Start Menu, then Control Panel, then Game Controllers. Select from the list which Controller you have. If you do not know, check your box or look on the internet. And no, Nintendo 64 Controllers do, sadly, not work.
Remember, use an Arcade Controller, or you will have a lot of unused buttons and controls.