The difference on the drive train side is that you have to be cautious about not getting in the way of your chain. My chain guard has a handy attachment I used as a guide for where to cable tie it, but most modern chain guards won't have that. Aim for a spot just behind where your pedal travels. You've already got the chainguard (I hope!) to partially protect you. You're aiming to keep your skirt from wrapping around the seat stay or rear cog. Again, start with the straight line from chain stay to fender stay, and then add the seat stay and second fender stay cable ties.