The original (un-lit) clear plastic frame concept & design is by saul, who led an intersession class at the MIT Media Lab in 2003 (?) where about 10 students each designed and built a clear plastic bicycle frame. Some of the students modified the frame styling a bit, one of the other frames with a more curvy style is shown below.
After seeing one of the frames around MIT in 2004, I had the idea for customized edge lighting so I built up a frame and added the lighting effects.
The full project here is quite a lot of work unless you have a high-end machine shop at your disposal, but there should be several ideas for you along the way. I've included the CAD files for the plastic frame and the C code for the microcontroller. This is an "after the fact" documentation, i built this about 3 years ago.
As seen in the Wired Blog.
This article is brought to you by MonkeyLectric and the Monkey Light bike light