The tootophone could be the People's Instrument of the 21st Century. You don't need to learn sheet music or memorize fingering positions to play just about any melody with it. It can easily fit into a pocket, and it only costs about 25 cents to make. The basic 1 cc insulin syringe costs about 15 cents.
You can add pipe extensions to the body of the tootophone to give it a deeper, richer voice. A variety of tootophones could make some very interesting music, I'm sure.
To hear this tiny tooter in action, listen to the music samples in later steps.
Step 1: The Reed Material
From Wikipedia: "A reed is a thin strip of material which vibrates to produce a sound on a musical instrument. The reeds of most Woodwind instruments are made from Arundo donax ("Giant cane") or synthetic material; tuned reeds (as in harmonicas and accordions) are made of metal or synthetics."
Years ago, I borrowed a saxophone and couldn't get anything out of it except unmelodious squawks. As an experiment, I sanded down some PVC plastic and made a replacement reed for it. Still no great music, but at least it was easier to play. The sax got returned and I continued experimenting, mostly with PVC pipe body instruments.
Sanding PVC reeds was a lot of work, so I experimented with clear plastic packaging material I found in the trash. It came in different thicknesses and with different degrees of rigidity. Thinner material makes reeds that are easier to play. Plastic reeds can be cut out of scavenged packing material with scissors.
For your first tootophone, I suggest you go the easy route and just cut a reed out of scavenged plastic packaging material. You can make mellower sounding reeds out of rubber, but it is more complicated, since you have to make the material. (I haven't found off-the-shelf sheet rubber material for reeds yet.)
I found that the traditional cane reeds were at the stiff end of the spectrum, followed by different kinds of plastic and rubber at the other extreme. My first rubber reeds were made out of Sugru, a clay-like material that hardens like rubber. That eventually led to my present favorite, a combination of fiberglass mat material and silicone rubber.
I found that pure silicone rubber reeds were too floppy, so I increased their rigidity by adding cloth-like materials. In this step I explain how I make fiberglass and silicone rubber reed material. If you don't have the fiberglass, experiment with other synthetic cloth materials.
1. Start with a non-stick work surface, such as Teflon cloth, which I think is sold for kitchen use. What I use is a polyethylene plastic cutting board.
2. Cut a section of fine fiberglass mat material big enough to cut out the number of reeds you want to make. I usually make foot square sheets.
3. With a palette knife, or similar tool, spread out an area of silicone rubber on the work surface big enough for the fiberglass material and set the material onto the wet silicone. This eliminates any penetration problem from pressing the silicone through from above.
4. Start at the center with the palette knife and press down and toward the edges, forcing silicone from below up through the pores of the material. Make sure there is a reasonable layer of silicone on top.
5. If you want 2-ply material, or thicker, repeat steps 3 and 4. I use mostly 2 ply material.
6. Let it dry several hours, or overnight before peeling it up.
7. Cut it into strips and sections long enough to serve as the reeds. I use a paper cutter to cut the strips, which are about 1/4" wide.