Before starting make sure you have installed HomeBrew as per this Instructable:
Step 1: Install Wine
First order of the day is to get Wine installed.
It's a ridiculously easy process. In Terminal simply type:
brew install wine
Let it do its thing.
Once complete Wine is installed but there's a couple of steps to go though.
Step 2: Install Zenity
Zenity is a graphical system that Winetricks uses to make things a little easier.
Once again install is as simple as typing in:
brew install zenity
Let the install continue
Step 3: Install Winetricks
Winetricks installs a number of Windows components that certain Windows apps need.
If you haven't already guessed its a simple install:
brew install winetricks
Let the install complete.
We'll get to configuring Winetricks in another Instructable.
Step 4: Install XQuartz
XQuartz is a windowing system developed by Apple to allow UNIX applications to run in macOS. While not actively installed with macOS anymore it is once again a simple install only a slightly different install.
In Terminal type:
brew install Caskroom/cask/xquartz
This will download and install XQuartz in a similar way to the previous installs although it also does a couple of macOS side steps that the other apps don't do.