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It's been well over a year since the camper was constructed, no leaks have occurred. The fabric is still tightly glued to the plywood and the paint has no cracks. It's never been under any kind of cover has endured many rainstorms that are frequent here in North Alabama. There are many articles on the web about "Poor Man's Fiberglass", just do a Google search.
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I can't see where it would cause any issues. There would be no need to remove it for any of the things you mentioned, at least on my truck. All of the maintenance would be performed outside the bed of the truck.
Since the truck is a few years old and I don't intend to remove the camper unless I have to for some unforeseen reason, I just bolted it to the truck. I used 3/8" X 2-1/2" bolts, 5 on each side. I'll post photos here this weekend. You could also use clamps if you don't want to drill holes in your truck. Just search for "clamps for truck caps" on Amazon.
Cab-over Camper for PickupView Instructable »