What will I have to do to make this happen?
I built this just recently. Check out my write up on how to make LEDs blink when you strum your guitar Any questions, just ask!
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As lemonie and mathews suggest:
an amplifier circuit is necessary to switch the higher current necessary for the leds - it can be a directly linked with an amplifier transistor circuit or mosfet - or indirectly with an led colour organ sourced with a small electret microphone.
Hook the LEDS to some kind of Darlington Pair switch activated from the pickups and power off batteries perhaps?L
A MOSFET may be better as it can be easily configured to have a higher input impedance than a bi-polar transistor. Then with the signal from this, you could control the LED, or send it to some logic to control the LEDs.
Perhaps so, I was only thinking of what I've got.