0-max- 5 years ago Sure! You do whatever you want to do! So long you don't hold me responsible for shocks, burns, deaths, or worldwide power outages as a result. :P If what you are asking is if you can connect the negative of a DC power supply to neutral, most likely you can but it is NOT ADVISABLE.Do some research on the power supply you are using to see if the output is fully isolated from AC. Also consider once you do that you now have a circuit that is connected directly to mains, if the circuit has exposed metal or wires, that would be effectively the same as sticking a fork into the larger reciprocal hole and leaving it there, and hoping that your household wiring is correct and the plug is the right way around.