0Metal_maestro 5 years ago It all depends on how much compression is being 'lost.' I know of a few vehicles that I have driven that have multiple cylinders that are missing but it still performs well enough. The age of your car will also make a difference. Computerized engines tend to not like anything that isn't optimum. Where an older car will shrug and get on with its life.If your car is making a blue smoke screen and is gutless while driving. There is a good chance you have bad no go and die kind of compression loss.