i would use a ported box my cousin has a 2000w amp and 4-15"kickers and it hits hard
the first thing you should check is the compatibility,check your amp, it should say how many ohms (can go from 2 ohms to 16 ohms)then check your speakers ohm value if they match continuei would never recomend putting an amplifier inside a box without any air circulation if its not made to do so.amplifiers heat up fast if you play them loud, so putting it inside a box with no air circulation will only make its life shorteralso, if your amp only has two outputs check this site to figure out how to plug your speakers http://www.termpro.com/articles/spkrz.html
You need 4.5-6.5 cubic ft of enclosed space. No port or venting. I guess you really want to hear that ipod don't cha.
Depends on the speakers to a large extent. Wo-cha got ? Steve